Enteric™ Capsule Drug Delivery Technology – Achieving Protection Without Coating

Some drug compounds are difficult or impossible to deliver orally due to the need for enteric protection, but cannot withstand the high temperatures associated with application of an enteric coating or are negatively affected by the coating solution or suspension.  This technical article describes the enTRinsic™ drug-delivery technology, which provides full enteric protection without the need for a separate enteric coating.  This innovative technology has proven enabling, allowing the oral delivery of sensitive molecules and serving as a valuable product-development tool, simplifying and accelerating prototype development and rapid in vivo testing of products requiring enteric protection and/or targeted release to the upper gastrointestinal tract.