In what applications is liquid and semi-solid fill capsule technology used?

These technologies are highly versatile. Key formulation challenges that can be addressed using liquid and semi-solid fill technologies, in either liquid fill hard capsules or soft gel finished dosage forms, include bioavailability enhancement, high potency/low dose and API stability. These technologies provide straightforward and efficient encapsulation of difficult-to-formulate actives such as: low-melting point compounds, hot melts, high viscosity fills, solid dispersions, low-dose actives and highly potent actives. Specialized applications include coated liquid fill hard capsules for optimal drug delivery to the colon, and capsule-in-capsule technology for combination drugs or dual drug release profiles.