Lipid-Based Formulation Technology Technical Brief

Lipid-based formulation (LBF) approaches — encompassing the use of lipid excipients, solvents, co-solvents in liquid, semi-solid or solid formats — are a key tool for improving solubility. LBF is primarily used for bioavailability enhancement, along with addressing food effects and associated variability. Additionally, liquid or semi-solid LBF approaches are routinely utilized for low dose/highly potent applications, due to the ability to achieve uniform API distribution at low dosing, and to minimize exposure hazard.

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