Interest in pulmonary delivery of drugs is increasing for acute and systemic diseases. For many APIs considered for lung delivery, particle engineering via spray-drying is an enabling technology. This webinar describes how target product properties and delivery profiles can be met by altering spray-drying process conditions and excipient selection for inhalable dry powders. Topics include key considerations for formulating with crystalline or amorphous materials, methods to tailor spray-drying conditions to ensure physical and chemical stability of the API, approaches to increase process throughput and efficiency, selection criteria for formulation excipients to ensure physical stability and aerosolization, and analytical testing considerations.
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