lipid multi-particulates

With a growing awareness across the globe for healthy aging, sports nutrition, and clean label products, consumers are looking for health and nutritional products that deliver improved performance that meet their individual needs. As demand continues to expand, supplement manufacturers are seeking innovative ingredients and dosage form solutions to bring new and improved products to market. 

Leveraging our long experience in pharmaceutical delivery science, we developed a Lipid Multiparticulate (LMP) technology to improve the performance of nutritional actives that enhance bioavailability, achieve taste masking and enable modified release. Through this technology, we have enabled our customers to bring new and improved nutritionals to market.

What are Lipid Multi-Particulates?

Lipid Multiparticulates (LMP) are an innovation originally developed to enhance the performance of pharmaceutical products. This technology is now available for consumer health and nutrition applications and can help to improve the performance of active nutritionals in three ways:

  • Modified Release
  • Taste Masking
  • Bioavailability

Lonza’s proprietary Melt Spray Congeal (MSC) manufacturing process is used to produce LMP’s. They are spherical in shape and characterized as microspheres formulated to contain discrete units of active nutritional ingredients including:  botanicals, vitamins and amino acids. The process allows for tighter control of particle size ranging from 50 – 300 microns. The ability to precisely deliver a metered dose of actives combined with the controlled particle size of LMP helps to improve gut distribution. This advanced technology is aligned with growing consumer demand for clean label products through a solvent-free manufacturing process.

A Broad Range of Finished Dose Formats

LMP microspheres have excellent flow properties, making them ideal for inclusion into a broad range of finished dose formats including:

  • Microspheres in Bulk Powder Blends
  • Sachets
  • Orally Disintegrating Tablets (ODTs)
  • Microspheres in suspension
  • Microsphere + liquid combinations

Manufacturing Footprint and Capabilities:

In addition to our pharmaceutical development and manufacturing site, Lonza has installed capacity exclusively for the nutrition market in Greenwood, SC with a co-located product development team ready to assist in the ideation of custom formulations. This site is serving development and manufacturing in both the Americas and European markets.